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Researchers at Â鶹Ãâ·Ñ°æÏÂÔØBoulder, led by Biochemistry Professor Robert Batey , have developed compositions and methods for temporal regulation of single guide RNAs (sgRNAs) that comprise a small molecule-binding aptamer in the sgRNA, which enables small-molecule-dependent gene editing in bacteria. They also developed a method for selecting sgRNAs that are...

Dr. Celso Espinoza is a senior drug discovery investigator with the biopharmaceutical firm AbbVie. Originally a component of Abbott Laboratories, AbbVie split in 2013 to focus on new drug discovery, and Celso followed. Since then, Celso has been a part of many major therapeutic breakthroughs including the immunosuppressor Humira, and...

Graycen Wheeler is a 6 th year graduate student in BCHM's Liu Lab. She was initially attracted to Â鶹Ãâ·Ñ°æÏÂÔØBiochem by the strong web presence and diversity of research in the department’s labs. During graduate recruitment, “the interview process wasn’t nearly as anxiety-inducing and I felt natural interacting with grad...

Otto Kletzien likes to stay busy. He’s a Signaling and Cellular Regulation (SCR) fellow, one of approximately 15 in the department, an active participant and former leader of Â鶹Ãâ·Ñ°æÏÂÔØBoulder’s RNA Club chapter, for which he ran operations and finance, a contributor to the Synthetic Biology Journal Club, and he’s...

Local Roots First up in our Be a Biochemist series is undergraduate Yannick Lee-yow, a Biochemistry (BCHM) and Molecular, Cellular, and Developmental Biology (MCDB) double major who had a round-about path into biochemistry. He found a home conducting independent research with MCDB’s Dr. Ding Xue for the past four years...

Scientists have been studying cyanobacteria and its many potential applications for decades, from cutting CO2 emissions to creating a substitute for oil-based plastics, but there wasn’t a deep understanding of the full life cycle and metabolism of specialized compartments within these common bacteria – until now.

Alumnus worked in lab of Distinguished Professor Marvin Caruthers assisting in the development of pioneering technology

When do cells decide to divide? For 40 years, the textbook answer has been that this decision occurs in the first phase of a cell’s existence – right after a mother cell divides to become daughter cells. But researchers at Â鶹Ãâ·Ñ°æÏÂÔØBoulder have found that it’s actually the mother cell...

In a study published today, a team at Â鶹Ãâ·Ñ°æÏÂÔØBoulder took advantage of a new microscopic technique to follow the lives of individual bacteria as they grew and divided in complex colonies.

Moshe Gordon, a Biochemistry graduate student in Dr. Joseph Falke's lab has been awarded the SRAA Outstanding Poster Award at the 2020 Biophysical Society Annual Conference in San Diego, California. Moshe presented his poster, titled "Single-Molecule Diffusion Studies of Membrane-bound PDK1-PKC Heterodimers Reveal a Monomee-Dimer Equilibrium with Regulatory Significance," during...